Goji berry health benefit review, dosage, supplement research studies
Side effects, safety
For vision improvement, antioxidant, does it help with blood pressure, weight loss, diabetes, cancer, and fertility?
You will find this fruit marketed as Himalayan or Tibetan source
February 1 2017

Health benefit, review
Goji berry has been used for centuries in Asia for eye health benefit and to maintain vitality. We are not aware of any long term published research regarding the use of this supplement in humans or the benefit of drinking the juice daily. There are countless claims when one searches online for goji berry, but most of these claims are premature and not based on results of human studies. The plain fact is research in humans is lacking, at least in the Western world.

However, just because research is minimal does not mean this berry has little benefit. In fact it is, in our opinion, a superfood. Many people notice improvement in vision since it has high amounts of substances that benefit visual health.

Buy Goji Berry, 500 mg each pill

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Goji berry 500mg, 60 capsules
Supplement Facts
Amount Per Serving:
Goji Berry 500 mg

Suggested use: As a dietary supplement, take one to three goji berry capsules a few times a week or as recommended by your health care provider.

 

Other beneficial fruit, berry and herbal products
Learn about the latest studies regarding the benefits of pomegranate, mangosteen, graviola, acai, goji, mangosteen, Green Tea Extract and other popular fruit and herbal extract products.

Claims made about this product
Some of the online goji berry health benefit claims include such promises as, “Would you believe the average woman in the Himalayan Hunza tribe lives to be 100? And that arthritis, chronic fatigue syndrome, sexual or erectile dysfunction and depression are totally unknown to them? Their secret? The berry of the goji vine.”

We do believe that it has health benefits and future research will indicate which of the goji marketing claims will turn out to be accurate and which will turn out to be overly enthusiastic. For the time being it appears that one health benefit that has promise is in the realm of vision health. Goji berry has a high level of zeaxanthin which is a carotenoid, along with Lutein, necessary for optimal eyesight. We would suggest, though, rather than consuming goji berry predominantly, it would be a good idea to consume a variety of berries – cranberry, blueberry, strawberry, maqui, etc – in order to ingest a number of different phytonutrients.

Goji berry side effects, safety, danger, risk
As of 2017, no goji berry side effects have been reported in the medical literature. High doses could induce alertness at bedtime and perhaps interfere with optimal sleep. As to goji juice side effects, it is difficult to expect any problems with drinking a couple of ounces a day unless it is mixed with other fruits that you may have an allergic reaction to.

Benefits found through studies

Vision and eyesight
Goji berry is well known for having high nutritional value. Research shows it contains many vitamins, minerals, carotenoids and flavonoids that support Eyesight and Vision health. Some of these nutrients include vitamins A, C and E, and carotenoids, beta-carotene, lutein and zeaxanthin. Goji berry is one of nature’s richest sources of zeaxanthin and important nutrient to visual function and retinal health. It contains about 100 to 200 mg of zeaxanthin per 100 grams.

Antioxidant
Lycium barbarum goji juice improves in vivo antioxidant biomarkers in serum of healthy adults.
Nutr Res. 2009.
Although Lycium barbarum goji and active compounds have a high in vitro antioxidant score as determined by simple chemical reaction methods, their in vivo antioxidant effects in humans have not been extensively examined. After our earlier report that a Lycium barbarum preparation (GoChi) helps prevent oxidant stress-related conditions in humans, our present study examined the hypothesis that the antioxidant effects of GoChi result from its ability to enhance endogenous antioxidant factors. We investigated the effects of GoChi in a 30-day randomized, double-blind, placebo-controlled clinical study. The study population included 50 Chinese healthy adults aged 55 to 72 years. In vivo antioxidant markers, consisting of serum levels of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and lipid peroxidation were examined preintervention and postintervention with goji or placebo. Our results indicate that goji increased antioxidant efficacies in humans by stimulating endogenous factors and suggest that continued use beyond 30 days might help prevent or reduce free radical-related conditions.

Protection of heart tissue from chemotherapy drug toxicity
Protective effect of Lycium barbarum on doxorubicin-induced cardiotoxicity.

Phytother Res. 2007.
In rodents given doxorubicin, a drug used in chemotherapy, goji berry administration reduced the toxicity to heart muscle from the drug. The antitumor activity of doxorubicin was not compromised by goji berry, which allows it to be used together with the drug.

Information
Goji berry is a fruit popular in Tibet and the plant also grows in Mongolia and China, and probably in India and Thailand. The plant is known in China as wolfberry or Lycium berry. A search on Medline in 2017 revealed only a few human studies. This fruit and tree are also known as Gouqizi, Fructus Lycii, and Wolfberry.

Ingredients and substances in the plant
Goji berry has polysaccharides, betaine, cerebroside, beta-sitosterol, p-coumaric, various vitamins, and carotenoids such as beta carotene and zeaxanthin. The name goji appears to be an English contraction of the Mandarin name, gouqi (pronounced goo-chee) or Gou Qi Zi.

Additional research
Goji berry study by FreeLife, who have their own branded goji product, shows health benefits
A randomized, double-blind, placebo-controlled, clinical study of the general effects of a standardized Lycium barbarum Juice, GoChi.
J Altern Complement Med. 2008.
This randomized, double-blind, placebo-controlled clinical trial is the first study reported from outside China that has examined the general effects of the orally consumed goji berry, Lycium barbarum, as a standardized juice (GoChi; FreeLife International LLC, Phoenix, AZ) to healthy adults for 14 days. Significant differences between day 1 and day 15 were found in the GoChi group in increased ratings for energy level, athletic performance, quality of sleep, ease of awakening, ability to focus on activities, mental acuity, calmness, and feelings of health, contentment, and happiness. GoChi also significantly reduced fatigue and stress, and improved regularity of gastrointestinal function. In contrast, the placebo group showed only two significant changes (heartburn and happiness). No significant changes in musculoskeletal or cardiovascular complaints were observed in either group. All parametric data (body weight, etc.) were not significantly different between groups or between day 1 and day 15 for either group. Our results clearly indicate that daily consumption of GoChi for 14 days increases subjective feelings of general well-being, and improves neurologic / psychologic performance and gastrointestinal functions. The data strongly suggest that further research is indicated to confirm and extend knowledge of the potential effects of Goji berry upon human health.

Animal studies
Goji berry, when given to animals, has been found to protect heart tissue from chemotherapy drug damage, to protect brain cells from oxidative harm, and to protect the liver from alcohol excess.

Protects brain and eye cells
An in vitro study with neuronal cell cultures shows polysaccharides extracted from goji berry can protect neurons against beta-amyloid peptide toxicity and protect retinal ganglion cells.

Exp Eye Res. 2014. High glucose-induced barrier impairment of human retinal pigment epithelium is ameliorated by treatment with Goji berry extracts through modulation of cAMP levels.

Goji berry research, benefit for cancer prevention
Effect of lycium barbarum polysaccharide on human hepatoma QGY7703 cells: inhibition of proliferation and induction of apoptosis.
Life Sci. 2005.
The study suggests that the induction of cell cycle arrest and the increase of intracellular calcium in apoptotic system may participate in the antiproliferative activity of wolfberry in human hepatoma cells.

Questions
Q. I have read some of your comments regarding goji juice and extract. I take the Freelife goji juice, 2 ounces in the morning and the same at night. After just a few days of taking the new goji juice I had a big spike in my blood pressure. I don’t believe the juice would do this or am I wrong, my doctor here in Canada has told me to drop the goji because that is the problem and I am reluctant to do so because of the benefits it has given me. If you could give me more information on this goji juice and high blood pressure relationship  I would appreciate it. My blood pressure was always close to normal.
A. We don’t know exactly what is is in the goji juice by Freelife. There have not been clinical studies that we know of in humans to know how it affects blood pressure. In general any good thing can turn bad if used in excess. It is possible that too much goji juice could increase blood pressure in some people. But until actual human studies are done regarding its influence on blood pressure, we can’t say with certainty.  There are many other beneficial fruit and vegetables juices and it is a good idea to have a wide variety rather than too much of just one type.